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CLINICAL STUDIES


                                                             Clinical study II: Wrinkle reduction
                BEFORE                                       Designed to investigate the effectiveness of


                                                             VERISOL on wrinkle reduction.
                                                                     ®
                                                             Study Design
                                                             // Double-blind, placebo-controlled trial
                AFTER                                        // 114 women aged 45-65


                                                             // Daily intake of 2.5g VERISOL  vs. placebo
                                                                                        ®
                                                             // Duration: 8 weeks, measurement after
                                                               4 and 8 weeks and 4 weeks washout
                 VERISOL  significantly reduces wrinkles:
                        ®
                The collagen in the skin increases by 60 %.
                                                             Results
                                                             // Significant reduction of wrinkle volume
             Procollagen accumulation in sub- epidermal fluid (rel. to baseline)  1,2       pro-collagen
                     VERISOL ®  (2,5 g/day)
                                          Placebo
                1,8
                                                             // Significantly increased concentration of

                                                             // Significant increase in skin elastin



                0,6
                    Baseline  End of    Placebo  End of
                            treatment         treatment      Proksch et al. (2020). Positive effect of fish-derived Bioactive
                                                             Collagen Peptides on skin health. Nutrafoods, 1:127-133.
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